Biochemistry (BIOC)

BIOC 545. Biochemistry I3 Units

Term Typically Offered: Fall Only

Description: Chemistry of amino acids, protein structure and function; metabolism of carbohydrates, fats and amino acids.

Note: Credit may not be earned in both BIOC 545 and BIOC 645.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 547. Advanced Biochemistry II3 Units

Term Typically Offered: Spring Only

Prerequisite(s): BIOC 545 Biochemistry of nucleotides and nucleic acids; RNA, DNA and protein biosynthesis, biomembrane phenomena, enzyme properties, kinetics, and control mechanisms; ligand binding.

Description:

Note: Credit may not be earned in both BIOC 547 and BIOC 647.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 603. Special Topics in Biochemistry1-4 Units

Prerequisite(s): BIOC 645 and BIOC 647 (or concurrently), or consent of instructor.

Description: Arranged to fit individual needs on topics of current interest or to receive some advanced training or conduct research project.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 606. Biochemistry Seminar1 Unit

Description: Both Fall and Spring semesters.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 611. Techniques in Biomolecular Interactions4 Units

Term Typically Offered: Fall Only

Prerequisite(s): Student must be registered in the graduate school.

Description: Biochemical, molecular, and bioinformatic techniques to understand cellular interactions, including chromatin associations that inform DNA structure, editing, and gene expression; protein-protein interactions; and protein: ligand associations that influence enzyme activity.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 613. Biochemistry Laboratory2-4 Units

Grading Basis: Pass/Fail

Description: The course will consist of participation in the research programs of two laboratories in the department. A half-semester will be devoted to each laboratory. Pass/Fail grading.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 619. Research1-15 Units

Grading Basis: Pass/Fail

Description: Biochemistry research.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 620. Scientific Method and Grant Writing2 Units

Grading Basis: Pass/Fail

Term Typically Offered: Spring Only

Prerequisite(s): Restricted to students in the Biochemistry and Molecular Genetics graduate programs; permission of course director.

Description: This objective of this course is to introduce students to the fundamentals of grantsmanship. The topics incorporate all aspects for grant application process as well as overview of the scientific method, generation of hypotheses, and research design. Student-directed learning is a major component for this course with the summative event being completion of a grant proposal. A reiterative writing process for proposal development will be ongoing throughout the course.

Note: May be repeated once for up to 4 credits.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 630. Responsible Conduct of Research: Survival Skills and Research Ethics1-4 Units

Grading Basis: Pass/Fail

Description: The topics covered include 11 areas of Research Compliance training mandated by the NIH for training grants and focuses on contemporary research ethics in biomedical sciences.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 640. Principles of Biochemistry5 Units

Term Typically Offered: Spring Only

Prerequisite(s): Consent of instructor.

Description: Covers general aspects of biochemistry with special emphasis given to areas applicable to dentistry. Topics include protein structure and function; chemistry and metabolism of carbohydrates, lipids, amino acids, and nucleotides; molecular genetics; nutritional biochemistry; calcification; and molecular endocrinology. Clinical conferences keyed to current lecture topics are presented by clinical faculty.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 645. Advanced Biochemistry I4 Units

Term Typically Offered: Fall Only

Prerequisite(s): Students must be registered in the graduate school.

Description: Chemistry of amino acids, protein structure and function; metabolism of carbohydrates, fats and amino acids.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 647. Advanced Biochemistry II4 Units

Term Typically Offered: Spring Only

Prerequisite(s): BIOC 545 or BIOC 645 or consent of instructor.

Description: Biochemistry of nucleotides and nucleic acids; RNA, DNA and protein biosynthesis, biomembrane phenomena, enzyme properties, kinetics, and control mechanisms; ligand binding.

Note: Credit may not be earned in both BIOC 547 and BIOC 647.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 648. Journal Club in Biochemistry and Molecular Genetics1 Unit

Grading Basis: Pass/Fail

Term Typically Offered: Fall Only

Description: This course will consist if student presentations of primary, peer-reviewed literature featuring current knowledge and techniques relevant to biochemical, molecular, and genetic understanding of molecular and cellular processes in health and disease.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 661. Molecular Mechanisms of Toxicology3 Units

Term Typically Offered: Spring Only

Description: Molecular interactions of drugs and toxicants on cellular processes; including foreign compound metabolism, signal tranduction, cell cycle, DNA repair/DNA replication are covered and put in context topics in molecular epedimiology.

Note: Crosslisted with PHTX 661.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 662. Biomedical Research Data Analysis Methods1 Unit

Term Typically Offered: Summer Only

Prerequisite(s): Currently enrolled graduate students in good standing.

Description: A lecture and discussion course designed for graduate students desiring to learn the basic statistical methods and data presentation approaches that are used in biomedical research.

Note: This course requires permission from the instructor.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 663. High-Throughput Sequencing Data Analysis3 Units

Term Typically Offered: Fall Only

Prerequisite(s): Students must be registered in the graduate school and are expected to have a basic understanding of molecular biology.

Description: Permission from the course director is needed for students not meeting these prerequisites. High-Throughput Sequencing Data Analysis will focus on current issues in bioinformatics, including: next generation sequencing; microRNA and mRNA integrative analysis; epigenetics, metagenomics, personalized genomics, and single cell sequencing.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 667. Cell Biology3 Units

Term Typically Offered: Spring Only

Prerequisite(s): One quarter of graduate level biochemistry or consent of instructor.

Description: An advanced treatment of contemporary cell biology including membrane structure and function, cytoskeleton, signal transduction, regulation of cell cycle, apoptosis, and molecular mechanisms of cellular differentiation. Graded.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 668. Molecular Biology3-4 Units

Term Typically Offered: Spring Only

Prerequisite(s): Student must be registered in the graduate school.

Description: Students are expected to have a basic understanding of molecular biology principles and protein structure. Best preparation for succeeding in the course is previous course in biochemistry and experience with reading scientific literature. Permission from the Course Director is needed for students not meeting these prerequisites. This course examines the fundamental principles of molecular biology as they apply to mechanisms controlling gene expression. Topics include: transcriptional and post-transcriptional regulation of gene expression; RNA and miRNA biology; and protein synthesis and regulation. An emphasis will be on student-directed learning requiring completion of pre-class reading, and in-class discussion of current literature.

Note: Crosslisted with BIOL 668.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 670. Biomedical Genetics and Genomics3-5 Units

Term Typically Offered: Fall Only

Prerequisite(s): Students must be registered in the Graduate School.

Description: This course examines the fundamental principles of genetics and genomics as they apply to biomedical research. Topics include: Mendelian, population, quantitative genetics, epigenetics, and bioinformatics. An emphasis will be on reading and critiquing current literature.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 675. Cancer Biology4 Units

Prerequisite(s): BIOC 545 or BIOC 645 or equivalents.

Description: A comprehensive course on cancer biology with emphasis on molecular mechanisms and research. Topics will include: the public health impact of cancer, molecular mechanisms of carcinogenesis and metastasis, host-tumor interactions, current and future molecular therapies and prevention, apoptosis, tumor immunology, cancer genetics and genomics, prevention, metabolism in cancer cells, signal transduction, cell cycle, and oncogenes and tumor suppressor genes. There will also be clinical-based lectures.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 680. Biomolecular Interactions2 Units

Prerequisite(s): BIOC 645 and BIOC 647 or equivalents.

Description: This course examines techniques used to characterize biomolecules and their interactions including surface plasmon resonance, equilibrium dialysis, microcalorimetry, analytical ultracentrifugation, dynamic light scattering and absorption fluorescence and circular dichroism spectroscopies.

For class offerings for a specific term, refer to the Schedule of Classes

BIOC 816. Special Project-Biochemistry1-16 Units

Description: This course is to be arranged to fit individual needs to cover topics of current interest or to participate in research projects or to receive some advance training.

For class offerings for a specific term, refer to the Schedule of Classes