Biochemistry and Molecular Genetics (PhD)

Doctor of Philosophy in Biochemistry and Molecular Genetics
Unit: School of Medicine (GM)
Department: Biochemistry and Molecular Genetics
Academic Plan Code(s): BIOCPHD, BIOCPHDBI

Program Information

As educators and scientists, the faculty of the Department of Biochemistry and Molecular Genetics subscribe to the following missions:

• Provide up-to-date and high-quality classroom and laboratory instruction in the disciplines of biochemistry, molecular biology, and genetics to students at the university.
• Conduct and publish research or other scholarship in areas that advance knowledge of a discipline, and contribute to improving the human condition.
• Train pre- and post-doctoral individuals in biomedical research.

Admission Requirements

All applications must be submitted using the online graduate application.

Doctoral students are admitted for Fall term only. Be sure to select Fall term for start date and Biochemistry and Molecular Genetics for the program. Rolling admission is used for the PhD program. Review of applications begins in December of each year. Applications are reviewed continuously through March.

Criteria and Mechanism for Selection

Criteria
The Biochemistry and Molecular Genetics department uses a holistic approach for reviewing applications and selecting candidates for interview. The applicant's academic record, research experience, and letters of recommendation are closely evaluated. Competitive candidates have a strong background in biochemistry, chemistry, or biology with evidence of rigorous coursework. In addition, a one-to-two-page personal statement describing past educational, laboratory and relevant life experiences, as well as a brief description of professional goals after the degree program, is required.

Competitive applicants have:

• A minimum undergraduate (and graduate) overall grade point average of 3.0 (4.0 system) with an average of 3.0 in science courses.
• Previous research experience
• Strong letters of recommendation

Selection
The Biochemistry and Molecular Genetics Department's Graduate Executive Committee (GEC) reviews and considers applications from December through March. Top candidates will be interviewed online or in person. Select candidates will be invited to a recruitment weekend in February to visit the department and meet faculty and students.

Select candidates are nominated for Integrated Programs in Biomedical Sciences (IPIBS). Fellowship awards for qualified applicants (https://medicine.louisville.edu/academics-programs/doctoral-programs/phd-program-academics-programs/ipibs).The department will notify applicants by email of their decision. All applicants who are accepted into the program must respond with their decision no later than April 15. In the absence of a response, after April 15 the position in the program and financial support is no longer guaranteed and may be offered to another applicant. The Biochemistry and Molecular Genetics Department accepts four to six students per year into the PhD program. 

Requirements for the PhD Degree in Biochemistry and Molecular Genetics

During PhD training students receive considerable guidance from their mentor, committee, and faculty members of the department. However, students need to recognize that individuals who pursue a biomedical graduate degree are expected to take full responsibility for their own scientific and professional development and to seek out and utilize all available resources for that goal.

Annual progress reports to document that a student is in good standing within the Biochemistry and Molecular Genetics department graduate program are required. The criteria for good standing in the graduate program are based on successful completion of milestones that indicate progression towards a degree. These milestones are the successful completion of:

1. All coursework with a minimum GPA of 3.0.
2. A minimum of two laboratory rotations.
3. Two seminar presentations.
4. Annual progress reports that indicate satisfactory progress.
5. PhD qualifying exam (QE).
6. Approved dissertation research proposal and committee meeting.
7. Annual research conferences with committee meetings in years three and beyond.

To fulfill all requirements for the PhD degree a student must

1. Complete a body of novel research (dissertation).
2. Publish, at minimum, one first author manuscript.
3. Write and defend a doctoral dissertation that is acceptable by the dissertation committee and Graduate School.

Student Support

An IPIBS Fellowship will provide stipend support for the first 23 months. Support after the first 23 months is the responsibility of the individual student's dissertation advisor. Students are also encouraged to seek extramural support.

Guidance for the Student

The Director of the Biochemistry and Molecular Genetics Graduate Program will serve as the first year advisor to all incoming graduate students until a dissertation advisor (mentor) is selected. During the first year, all students will meet with all available faculty to discuss potential research projects and complete a minimum of two laboratory rotations to help select a lab and mentor. After completion of lab rotations and before beginning a second year, the student will select a mentor, subject to the approval of the Graduate Executive Committee and the department chair.

PhD Qualifying Exam 

The PhD academic program must be completed by the end of year two.  Upon successful completion of all coursework, a student becomes eligible to take the PhD Qualifying Exam (QE).  The purpose of the QE is to evaluate the student’s ability to interpret literature, develop a research plan, integrate material from the graduate curriculum, display core knowledge of biochemical principles, and orally defend his/her ideas.  The format of the QE requires the student to write and orally defend a NIH-style fellowship proposal, followed by an oral exam covering general biochemical/genetic principles covered in the curriculum. Upon successful completion of the QE, a student becomes a doctoral candidate and may also be eligible to earn an MS degree.  An initial committee meeting should be held during the second year to provide guidance on the student’s research.  A full research proposal must be completed and approved by the committee before the end of the Spring term of the students year three.   

Curriculum

¹

Students seeking only the PhD must complete 42 minimum total hours to earn the degree.  Students in the MD-PhD program typically complete 24 minimum total hours to earn the degree.

Bioinformatics Specialization

Doctor of Medicine (MD) and Doctor of Philosophy (PhD) in Biochemistry and Molecular Genetics

Unit(s): School of Medicine
Program Webpage 
Academic Plan Code(s): MED_MD and BIOCPHD

On this Page

Program Overview
Admission
Dual Degree Requirements
Program of Study
Contact Information

Program Overview

The MD‑PhD in Biochemistry and Molecular Genetics prepares physician‑scientists to investigate the molecular mechanisms that shape human health and disease. The program integrates pre‑clinical medical study, advanced research training in biochemistry and molecular genetics, dissertation work, and clinical rotations. Students gain experience in laboratory investigation and patient care, supported by close faculty mentoring and access to extensive research and clinical resources. This dual‑degree option benefits students interested in careers that combine medical practice with molecular and genetic research, academic medicine, or innovation in biotechnology, pharmaceuticals, and other research settings. Students receive full tuition remission, a competitive stipend, and health insurance during the graduate research phase. For more information on program benefits and examples of student research and publications, visit the MD‑PhD Program website.

Admission

Applicants must meet the School of Medicine admission requirements and apply through the American Medical College Application Service (AMCAS), including submission of MCAT scores. Applicants indicate interest in the MD-PhD program within the AMCAS application. Selected applicants interview with both the School of Medicine Admissions Committee and the MD-PhD Program Committee. Research experience and interest in a physician‑scientist career are important considerations.

Current UofL medical students may apply after completing the second year of medical school by contacting the MD-PhD Program Director.

Dual Degree Requirements